Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC724H1135N213O203S5

DescriptionStandard

        MAKVQFKPRPATDFIVVHCAATKASMDIGVREIRQWHVQQGWLDIGYHFVIRRNGTVENGRPHDVIGSHVKSYNSRALGICLAGGIDDKGQPQNNFTPEQFASLKLLLIANKRQYPQAQIVGHHDLDSGKACPSFKVSDWLKTAGI
    

Molecular Weight16231.39 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)6.09

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0417

GRAVY Index-0.33

Hydrophobic Moment 0.68

Boman Index0.00

Instability Index32.94

Aliphatic Index 83.49

Aromaticity 0.0822

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6685.54

LogP -66.64

H-bond Donors 231.0

H-bond Acceptors 221.0

Rotatable Bonds 536.0

Heavy Atoms 1145.0

Ring Count 29.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191961 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudomonas phage phiPsa17 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic