Peptide Database

Peptide NameCRT2 p128 (YYIMFGPDI)

Function Ontology

Anticancer ▸ Tumor T-cell antigen

Immunology ▸ Epitope/vaccine antigen ▸ T-cell epitope

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC55H75N9O14S

DescriptionStandard

        YYIMFGPDI
    

Molecular Weight1118.30 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.1379

GRAVY Index0.62

Hydrophobic Moment 0.23

Boman Index0.53

Instability Index14.22

Aliphatic Index 86.67

Aromaticity 0.3333

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 365.09

LogP 0.87

H-bond Donors 12.0

H-bond Acceptors 14.0

Rotatable Bonds 31.0

Heavy Atoms 79.0

Ring Count 4.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0263440 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Immunomodulatory Anticancer Tumor antigen T-cell epitope HLA-A24-restricted CTL epitope

TargetHLA-A*24:02; HLA-A24-positive CRT2-expressing tumor cells

MethodIFN-γ ELISPOT; CTL induction assay; 51Cr release cytotoxicity assay