Peptide Database

Peptide NameHepcidin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC419H664N118O121S15

DescriptionStandard

        MKAFSIAVAVTLVLAFVCIQDSSAIPFQGVQELEEAGGNDTPVAAHQMMSMESWMESPVRQKRHISHISMCRWCCNCCKAKGCGPCCKF
    

Molecular Weight9771.45 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0077

GRAVY Index0.17

Hydrophobic Moment 0.54

Boman Index0.11

Instability Index63.93

Aliphatic Index 67.98

Aromaticity 0.0674

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3787.41

LogP -38.93

H-bond Donors 138.0

H-bond Acceptors 140.0

Rotatable Bonds 321.0

Heavy Atoms 673.0

Ring Count 15.0

Amide Bonds 95.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239492 VERIFIED: YES

Provenance & Taxonomy

OrganismParalichthys olivaceus [Animal]

FamilyHepcidin

Tax ID8255

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0270498 VERIFIED: NO