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MYP_004114
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Basic Information
[D-R4W4]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C68H90N24O9
Standard
Sequence
RRRRWWWW
Physicochemical Analysis
1387.60 Da
12.00
3.76
3.56
0.4700
-2.70
0.11
-0.86
295.15
0.00
0.5000
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
577.78
-0.26
25.0
13.0
39.0
101.0
8.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0147197 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
64 μg/mL
MIC
PMID25157458;28594345;30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25157458/
RECORD: Rec_0148415 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
21.7 μg/mL
MIC
PMID25157458;28594345;30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25157458/
RECORD: Rec_0149807 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Cyclization
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25157458 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25157458/
RECORD: Rec_0153745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lymphoblastic leukemia CCRF-CEM 70-80% Killing
50 μM
PMID25157458;28594345;30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25157458/
RECORD: Rec_0174182 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Pig kidney epithelial cells LLC-PK1
45 % killing at 100 μM
Cytotoxicity
PMID25157458;28594345;30360400 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25157458/
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