Peptide Database

Peptide NameLSPGV

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC21H37N5O7

DescriptionStandard

        LSPGV
    

Molecular Weight471.55 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0480

GRAVY Index1.04

Hydrophobic Moment 0.41

Boman Index0.51

Instability Index95.88

Aliphatic Index 136.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 191.16

LogP -1.83

H-bond Donors 6.0

H-bond Acceptors 7.0

Rotatable Bonds 12.0

Heavy Atoms 33.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080760 VERIFIED: YES

Provenance & Taxonomy

OrganismApostichopus japonicus [Animal]

Familysea cucumber intestine-derived peptide

Tax ID307972

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory Acetylcholinesterase inhibitory Antioxidant

TargetAChE; DPPH; Caenorhabditis elegans

Activity7.32 μM

MethodIC50