Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC249H397N63O81S4

DescriptionStandard

        MEKETTIIESIQEVSLEELDQIIGAGKNGVFKTISHECHLNTWVFLATCCS
    

Molecular Weight5697.45 Da

Isoelectric Point (pI)4.63

Net Charge (pH 7.0)-5.34

Net Charge (pH 7.4) -5.71

Charge Density (pH 7.0) -0.1047

GRAVY Index0.09

Hydrophobic Moment 0.49

Boman Index0.15

Instability Index31.87

Aliphatic Index 97.45

Aromaticity 0.0588

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2322.36

LogP -22.24

H-bond Donors 82.0

H-bond Acceptors 82.0

Rotatable Bonds 194.0

Heavy Atoms 397.0

Ring Count 6.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0123939 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus suis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria