Peptide Database

Peptide NameAntibacterial protein LL-37 (cathelicidin; primates, mammals,animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC204H335N61O54

DescriptionStandard

        LLGDFFRKAREKIGEEFKRIVQRIKDFLRNLVPRTES
    

Molecular Weight4506.22 Da

Isoelectric Point (pI)10.40

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1019

GRAVY Index-0.66

Hydrophobic Moment 0.97

Boman Index-0.29

Instability Index32.41

Aliphatic Index 92.16

Aromaticity 0.1081

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1928.05

LogP -14.74

H-bond Donors 69.0

H-bond Acceptors 58.0

Rotatable Bonds 159.0

Heavy Atoms 319.0

Ring Count 5.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412901 VERIFIED: YES

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

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