Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC384H618N102O97S8

DescriptionStandard

        MKSLVFVLVVLVLLSCVPPVRSGPNIYIRRLFSTCWRTKGVCKTSCGKSEIHHIFCDSAHLCCIDKKYLPVEFGK
    

Molecular Weight8472.16 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)6.69

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0892

GRAVY Index0.42

Hydrophobic Moment 0.80

Boman Index0.13

Instability Index65.02

Aliphatic Index 103.73

Aromaticity 0.0933

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3148.18

LogP -23.30

H-bond Donors 119.0

H-bond Acceptors 115.0

Rotatable Bonds 276.0

Heavy Atoms 591.0

Ring Count 15.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032732 VERIFIED: NO

Provenance & Taxonomy

OrganismUrsus arctos horribilis [Bacterium]

FamilyDefensin

Tax ID116960

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence