Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC913H1403N213O279S8

DescriptionStandard

        IDNLAEVDYSLNSLPAVFRQFIDLDLKGIVYPAGNYTGSTCVAAPFTIPDQSDSMLHLAFSEHIFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVFAVLPDSTTQLLFTMNIAANTSIALNIFDQKLVGSLCLNR
    

Molecular Weight20083.69 Da

Isoelectric Point (pI)4.13

Net Charge (pH 7.0)-13.07

Net Charge (pH 7.4) -13.46

Charge Density (pH 7.0) -0.0714

GRAVY Index0.37

Hydrophobic Moment 0.62

Boman Index0.25

Instability Index42.47

Aliphatic Index 100.22

Aromaticity 0.1148

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7793.22

LogP -85.16

H-bond Donors 266.0

H-bond Acceptors 276.0

Rotatable Bonds 644.0

Heavy Atoms 1413.0

Ring Count 32.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0266068 VERIFIED: NO

Provenance & Taxonomy

OrganismRostratula benghalensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria