Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC410H647N117O122S11

DescriptionStandard

        MKLAYVALAAAVVIACVCILQSAAVPFTQQTEDEHHVESGTPPTETSQEQTNPLAFFRVKRQSHLSLCRYCCNCCRNKGCGYCCKF
    

Molecular Weight9519.95 Da

Isoelectric Point (pI)8.06

Net Charge (pH 7.0)1.67

Net Charge (pH 7.4) 1.14

Charge Density (pH 7.0) 0.0194

GRAVY Index0.00

Hydrophobic Moment 0.66

Boman Index0.03

Instability Index55.89

Aliphatic Index 70.35

Aromaticity 0.0814

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 5095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3834.21

LogP -42.74

H-bond Donors 141.0

H-bond Acceptors 138.0

Rotatable Bonds 307.0

Heavy Atoms 660.0

Ring Count 14.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164405 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus grahami [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0395658 VERIFIED: NO