Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC164H271N51O55S2

DescriptionStandard

        KCNTATCATQRLANFLVRSSNNLGAILSPTNVGSNTY
    

Molecular Weight3901.34 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0740

GRAVY Index-0.13

Hydrophobic Moment 0.67

Boman Index0.01

Instability Index24.55

Aliphatic Index 79.19

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1755.88

LogP -26.66

H-bond Donors 63.0

H-bond Acceptors 60.0

Rotatable Bonds 126.0

Heavy Atoms 272.0

Ring Count 3.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152384 VERIFIED: YES

Provenance & Taxonomy

OrganismAiluropoda melanoleuca [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)