Peptide Database

Peptide NameFIRFamide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC51H78N14O12

DescriptionStandard

        SKPANFIRF
    

Molecular Weight1079.25 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.1621

GRAVY Index-0.27

Hydrophobic Moment 0.47

Boman Index-0.05

Instability Index5.21

Aliphatic Index 54.44

Aromaticity 0.2222

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 438.57

LogP -3.41

H-bond Donors 15.0

H-bond Acceptors 14.0

Rotatable Bonds 33.0

Heavy Atoms 77.0

Ring Count 3.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179392 VERIFIED: YES

Provenance & Taxonomy

OrganismDiploptera punctata [Animal]

FamilyFMRFamide related peptide

Tax ID6984

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0341494 VERIFIED: YES

Provenance & Taxonomy

OrganismDiploptera punctata [Animal]

FamilyFIRFamide

Tax ID6984

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0353832 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/