Peptide Database

Peptide NameHepcidin 2 variant 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC403H626N110O123S14

DescriptionStandard

        MKTFSVAVAVAVVLAFICLQESSAVPVTEVQELEEPMSNEYQEMPVESWKMPYNNRHKRHSSPGGCRFCCNCCPNMSGCGVCCTF
    

Molecular Weight9428.85 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-2.40

Net Charge (pH 7.4) -2.87

Charge Density (pH 7.0) -0.0282

GRAVY Index-0.01

Hydrophobic Moment 0.47

Boman Index0.07

Instability Index96.08

Aliphatic Index 58.35

Aromaticity 0.0824

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3698.00

LogP -40.47

H-bond Donors 133.0

H-bond Acceptors 137.0

Rotatable Bonds 301.0

Heavy Atoms 650.0

Ring Count 16.0

Amide Bonds 92.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0390710 VERIFIED: NO

Provenance & Taxonomy

OrganismDicentrarchus labrax [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence