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MYP_003895
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Basic Information
Gageotetrin B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
4 amino acids
C23H42N4O7
Standard
Sequence
LLLE
Physicochemical Analysis
486.60 Da
4.60
-1.23
-1.44
-0.3080
1.98
0.35
0.61
7.50
292.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
187.92
0.86
6.0
6.0
16.0
34.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0038955 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
linear lipopeptide with fatty-acid moiety
Bio-Activity Profile
Antimicrobial
MIC (reported 0.01–0.06 μM across gageotetrins A-C)
PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0189899 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antifungal
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0365365 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
linear lipopeptide with fatty-acid moiety
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive
MIC (reported 0.01–0.06 μM across gageotetrins A-C)
PaperPubMed PMID: 24502521 PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0371216 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Bacteriocin
1423
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
linear lipopeptide with fatty-acid moiety
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative
MIC (reported 0.01–0.06 μM across gageotetrins A-C)
PaperPubMed PMID: 24502521 PMID24502521 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24502521/
RECORD: Rec_0431414 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
linear lipopeptide with fatty-acid moiety
Bio-Activity Profile
Non-cytotoxic
human cancer cell lines
>30 μg/mL
GI50 cytotoxicity assay
PaperGageotetrins A-C, noncytotoxic antimicrobial linear lipopeptides from a marine bacterium Bacillus subtilis PMID24502521
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