Peptide Database

Peptide NameAlpha defensin (primates, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC417H655N119O131S4

DescriptionStandard

        MRTFALLTAVLLVALQAQAGPLQARCDEAAGQEQPGVDDQDISISFAWDKISALQASGERGQYEEPQSLQGWMGDRLWNRVSMVHVT
    

Molecular Weight9559.64 Da

Isoelectric Point (pI)4.50

Net Charge (pH 7.0)-5.40

Net Charge (pH 7.4) -5.70

Charge Density (pH 7.0) -0.0621

GRAVY Index-0.21

Hydrophobic Moment 0.60

Boman Index0.04

Instability Index48.90

Aliphatic Index 86.44

Aromaticity 0.0690

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 17990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4037.71

LogP -42.26

H-bond Donors 138.0

H-bond Acceptors 131.0

Rotatable Bonds 316.0

Heavy Atoms 671.0

Ring Count 13.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114095 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0368455 VERIFIED: NO

Provenance & Taxonomy

OrganismSaguinus labiatus [Animal]

FamilyDefensin

Tax ID78454

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal