Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC932H1424N208O284S7

DescriptionStandard

        KIDDLAEVDYSLSSSPAVFQPFIDLDLKGVFFPAGNYTDSPYVAASLTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFTVTIVEEACSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMSTEIPIISLQKDSFTVQIQGSMEVLAVLPDSTIQSLFTLNIVANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight20310.95 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-12.24

Net Charge (pH 7.4) -12.52

Charge Density (pH 7.0) -0.0665

GRAVY Index0.36

Hydrophobic Moment 0.55

Boman Index0.25

Instability Index49.38

Aliphatic Index 99.62

Aromaticity 0.1304

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7804.37

LogP -85.58

H-bond Donors 266.0

H-bond Acceptors 279.0

Rotatable Bonds 651.0

Heavy Atoms 1431.0

Ring Count 34.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346179 VERIFIED: NO

Provenance & Taxonomy

OrganismErithacus rubecula [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria