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MYP_003828
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Basic Information
Nigrosin-OG21 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Adverse immune reactivity ▸ Histamine-release modulation
Immunology ▸ Innate immune modulation ▸ Mast cell modulation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C87H157N23O24S2
Standard
Sequence
GLLSGVLGVGKKVLCGLSGLC
Physicochemical Analysis
1973.45 Da
8.90
1.74
1.50
0.0828
1.36
0.45
0.46
-2.60
152.86
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
737.82
-6.77
28.0
28.0
68.0
136.0
0.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0179317 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
18.75 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0188553 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
4.68 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0282789 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
4.68 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0304011 VERIFIED: YES
Provenance & Taxonomy
Odorrana grahami [Animal]
Nigrocin
167935
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
9.37 μg/mL
MIC
PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
RECORD: Rec_0389564 VERIFIED: YES
Provenance & Taxonomy
Odorrana margaretae [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 29213
16-32 μg/mL
MIC
PaperAssociating biological activity and predicted structure of antimicrobial peptides from amphibians and insects
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