Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC374H640N112O107S11

DescriptionStandard

        MALSVQIRAACLLLLLLVSLTAGSVLPSQTRQLTDLRTQDTAGATAGLTPVAQRLRRDTHFPICIFCCGCCRKAICGMCCKT
    

Molecular Weight8770.48 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.10

Charge Density (pH 7.0) 0.0671

GRAVY Index0.55

Hydrophobic Moment 0.66

Boman Index0.11

Instability Index40.33

Aliphatic Index 105.98

Aromaticity 0.0244

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3498.41

LogP -38.50

H-bond Donors 134.0

H-bond Acceptors 125.0

Rotatable Bonds 289.0

Heavy Atoms 604.0

Ring Count 6.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0037198 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyHepcidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. epidermidis (Gram-positive)

RECORD: Rec_0110704 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyHepcidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0177035 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyHepcidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetN. cinerea (Gram-negative)

RECORD: Rec_0338682 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyHepcidin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)