Peptide Database

Peptide NameColicin pyocin immunity family protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length601 amino acids

Chemical FormulaC2961H4730N840O878S16

DescriptionStandard

        MLYYEPEFLGSLRQEAYNTYEIAKTEREVAERNRVQKKPFGLFIEEMTLQKTLTDSQVAETAAHIILLESTLTLLRQEEGQAWHQCEHLIRIRGNKKFKYLHEVHGLRKLAQAKQGEIDVINQSIAKLKTEEMGLLMQQQRVNADLETAKITEPQRVENARLTVEAAEKAARDRRISEEIAATEAKRQRMENERLAEQERQRVEGTKQQVSEASCAQQASAWQNRFTLPALQPSGSAQYSFAASGMSAVVLSLREAAELHNSFLAAQEQLSAIATISASGSVAAMIALGIYQTKVGESSERPPGWNVNPKFVGSISLSAMGLPATESLASQGEMALPVRMRIIDAKDWIGCTEIYAVKTGVAGVLPKVKVGAVQYDESTGVYTFTTDSTPPRTLIFTPAQPPGAETRPILAPPGSTPATLQHTGEMIIKPVITPTILPLPQLYARDFHDYIIWFPADSGLEPVYVYLKSPRDEPGVVTGHGERITGIWLAGAGKDMGGPIPAQIADKLRGRQFSHFGRFRAAFWKVVGEDPNLVKYFKSGNLGNIKNGKAPSPKEREQVGRRVKYELHHLKPISKNGAVYHIENIRVLTPKRHMDIHKGVE
    

Molecular Weight66657.37 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)6.89

Net Charge (pH 7.4) 5.69

Charge Density (pH 7.0) 0.0115

GRAVY Index-0.38

Hydrophobic Moment 0.59

Boman Index-0.02

Instability Index45.61

Aliphatic Index 84.63

Aromaticity 0.0682

Extinction Coeff. Reduced 63830.00

Extinction Coeff. Oxidized 63955.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044869 VERIFIED: YES

Provenance & Taxonomy

OrganismYersinia pseudotuberculosis serotype O:1b [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)