Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length437 amino acids

Chemical FormulaC2176H3514N556O614S19

DescriptionStandard

        MMFLWCVLVLVSLLSVATGTSAGVKARITQKVLEYGRAIGIESLQQKLRTIQLKDVSGTEKLDIGKVEYSITGMQIVNLGLPKSALRLVPGTGVMLSVGDAYISLRGNWRVKYSWIIKASGSFELAVSELAISTIIAVKSDVTGRPTVSVTKCEAAVGSVKVRFHVSHTIYLLFQICSLVTASIAEMNHNLKTLNVLAKVDQYAELEYSMVESPVISNAMIDLGLKGEFYNIGPHEEPPFSPRPFLLPSQDTNMLYIGVSAFSINSAGFVYHRAGALRLYITDDMIPSGSLNRLNTKTFGKFIPQIAKMSPGLMMKLLVETVKEPIITLEPNNMTVQASSKVTAYAIQPNSILSPLFVLRLEASVIYMYTARCDLAESYVGPFQVRSLEDIFTTVVKDVIIPKVNAGVKQGYPLPAIGKMQLVKSHLQVLKVSLHLY
    

Molecular Weight47897.77 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)10.10

Net Charge (pH 7.4) 9.36

Charge Density (pH 7.0) 0.0231

GRAVY Index0.30

Hydrophobic Moment 0.75

Boman Index0.18

Instability Index31.22

Aliphatic Index 111.69

Aromaticity 0.0778

Extinction Coeff. Reduced 41830.00

Extinction Coeff. Oxidized 42080.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0397798 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus rhinocerous [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria