Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC731H1179N203O204S5

DescriptionStandard

        MHISEKGLVLIKRYEGLRLKAYQCSAGRWTIGYGHTHNIRAGDVITQQQAEAFLREDIAQVMALLNTQIKVPLTQNQCDALCSLVFNIGATAFAASTLLKKLNFGDYSGAAAEFIKWNKATVNDKKIPLLGLIKRRQVEKALFELA
    

Molecular Weight16235.74 Da

Isoelectric Point (pI)9.48

Net Charge (pH 7.0)6.74

Net Charge (pH 7.4) 6.29

Charge Density (pH 7.0) 0.0462

GRAVY Index-0.01

Hydrophobic Moment 0.64

Boman Index0.06

Instability Index34.76

Aliphatic Index 103.70

Aromaticity 0.0822

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6609.35

LogP -58.46

H-bond Donors 231.0

H-bond Acceptors 219.0

Rotatable Bonds 554.0

Heavy Atoms 1143.0

Ring Count 19.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023969 VERIFIED: YES

Provenance & Taxonomy

OrganismBacteriophage APSE-7 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0196246 VERIFIED: NO

Provenance & Taxonomy

OrganismCandidatus Hamiltonella defensa [Fungus]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence