Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC361H582N102O87S9

DescriptionStandard

        MPGAMKIFFFIFAALILLAQIFQARTAIHRALICKRMEGHCEAECLTFEVKIGGCRAELTPYCCKRRKKH
    

Molecular Weight8031.70 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)6.71

Net Charge (pH 7.4) 6.24

Charge Density (pH 7.0) 0.0959

GRAVY Index0.28

Hydrophobic Moment 0.44

Boman Index0.07

Instability Index46.65

Aliphatic Index 89.43

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3020.80

LogP -19.69

H-bond Donors 113.0

H-bond Acceptors 106.0

Rotatable Bonds 271.0

Heavy Atoms 559.0

Ring Count 12.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207084 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic