Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length513 amino acids

Chemical FormulaC2610H4054N650O750S16

DescriptionStandard

        MLPPLEMHTKIVGVLWRCFFLWNLYTSSAQTIYPGIKARATQRALDYGIQAGMEMIEQMLKEKNIPDLKGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTDWEIKSPLFQDTGGADLFLSGVYFTGIIVLARNDFGHPILKLQDCYAQVNHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIMNEVEALNANLSTIEVLTKIDNYTLLDYSLISSPEITENYINLNLKGVVYPLEDLTDPPFSPVPFVLPERSDSMLYVGISEFFFKSASFAYFTAGAFNVTLSTKEISNHLVQNSQGVGNVLSRIAEIYILSQPFLVRVMATEPPVISLLPGNFTLDIPASIMILTQSKNSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGILPLANAKLQQGFPLPNPHKISFVNSDIEVFEGFLLISTDLKYETSLKQQPSFHGWEGLNFINGQWRGKPAA
    

Molecular Weight57051.05 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-11.69

Net Charge (pH 7.4) -12.54

Charge Density (pH 7.0) -0.0228

GRAVY Index0.15

Hydrophobic Moment 0.67

Boman Index0.18

Instability Index38.33

Aliphatic Index 103.57

Aromaticity 0.1053

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51590.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0068557 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx canadensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria