MYP_003550
Basic Information
Wollamide- B
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Mycobacterium
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XLLVNX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0035491 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
cyclic peptide [Cyclic]
all-D amino-acid peptide [D]
None
None
First residue is D- phenyalanine, Third is D-leucine and sixth is D-ornithine
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv
40 μM
MIC
RECORD: Rec_0088488 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(1)=D-4-Cl-Phe; l=D-Leu; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
RECORD: Rec_0180324 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1,6
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
40 μM
MIC
RECORD: Rec_0240846 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 1,6
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
80 μM
MIC
RECORD: Rec_0309655 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
x(1)=D-4-Cl-Phe; l=D-Leu; x(6)=D-Orn
Bio-Activity Profile
Antimicrobial Anticancer
HepG2
100 μM
IC50
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