Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC499H796N140O147S9

DescriptionStandard

        MKPCLMTISILLILVHKTPGGLFRPYYGKSQEESWNPCQLHQGTCRNACRKNELQYLTCLNHEKCCLKFFVKVQSANNVKQESNSNPSLSVTTLSNYSQI
    

Molecular Weight11397.09 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)5.69

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0569

GRAVY Index-0.38

Hydrophobic Moment 0.53

Boman Index-0.03

Instability Index49.61

Aliphatic Index 78.90

Aromaticity 0.0800

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4676.50

LogP -51.24

H-bond Donors 165.0

H-bond Acceptors 165.0

Rotatable Bonds 380.0

Heavy Atoms 795.0

Ring Count 17.0

Amide Bonds 115.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326160 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0386071 VERIFIED: NO

Provenance & Taxonomy

OrganismBison bison bison [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin