Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 6.2

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC145H239N45O47S8

DescriptionStandard

        VSCTGSKDCYAPCRKQTGCPNAKCINKSCKCYGC
    

Molecular Weight3621.24 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.65

Net Charge (pH 7.4) 4.31

Charge Density (pH 7.0) 0.1367

GRAVY Index-0.49

Hydrophobic Moment 0.56

Boman Index-0.17

Instability Index60.97

Aliphatic Index 25.88

Aromaticity 0.0588

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1506.22

LogP -22.48

H-bond Donors 60.0

H-bond Acceptors 60.0

Rotatable Bonds 118.0

Heavy Atoms 245.0

Ring Count 4.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055166 VERIFIED: YES

Provenance & Taxonomy

OrganismScorpio maurus palmatus [Animal]

FamilyPotassium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide3-24; 9-29; 13-19; 31-34

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense

RECORD: Rec_0081170 VERIFIED: NO