Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC398H619N111O108S12

DescriptionStandard

        MTLRRKMSSFVFAFFILVQFLSECQAGLEYSEPLPGGEFAPCERCWLGRGTCRRMCTEDEKVIGQCRMNFFCCRPKIN
    

Molecular Weight9071.63 Da

Isoelectric Point (pI)8.50

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.09

Charge Density (pH 7.0) 0.0313

GRAVY Index-0.07

Hydrophobic Moment 0.57

Boman Index-0.02

Instability Index66.06

Aliphatic Index 60.00

Aromaticity 0.1282

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3533.60

LogP -31.27

H-bond Donors 132.0

H-bond Acceptors 123.0

Rotatable Bonds 299.0

Heavy Atoms 629.0

Ring Count 15.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409676 VERIFIED: NO

Provenance & Taxonomy

OrganismMustela putorius furo [Animal]

FamilyDefensin

Tax ID9669

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal