Peptide Database

Peptide NameArasin 1 (Ara-1) (Proline-rich antimicrobial peptide) (PR-AMP) (Pro-rich AMP)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC320H506N100O78S7

DescriptionStandard

        MERRTLLVVLLVCSCVVAAAAEASPSRWPSPGRPRPFPGRPKPIFRPRPCNCYAPPCPCDRWRH
    

Molecular Weight7226.52 Da

Isoelectric Point (pI)10.19

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.17

Charge Density (pH 7.0) 0.1177

GRAVY Index-0.32

Hydrophobic Moment 0.45

Boman Index-0.11

Instability Index94.48

Aliphatic Index 62.50

Aromaticity 0.0781

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2764.00

LogP -25.22

H-bond Donors 102.0

H-bond Acceptors 94.0

Rotatable Bonds 209.0

Heavy Atoms 505.0

Ring Count 21.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405359 VERIFIED: YES

Provenance & Taxonomy

OrganismHyas araneus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Gram-negative Hemolytic

TargetE. Coli (Gram-negative)