Peptide Database

Peptide NameCrotalus atrox antivenin

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC219H343N69O63S2

DescriptionStandard

        LLRRKSHDHAQNHDGDKCLRGASLGYYQSFLNQYKPQCILNKP
    

Molecular Weight5014.62 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)4.00

Net Charge (pH 7.4) 3.60

Charge Density (pH 7.0) 0.0930

GRAVY Index-1.06

Hydrophobic Moment 0.55

Boman Index-0.25

Instability Index47.41

Aliphatic Index 68.14

Aromaticity 0.0930

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2178.67

LogP -23.73

H-bond Donors 76.0

H-bond Acceptors 72.0

Rotatable Bonds 168.0

Heavy Atoms 353.0

Ring Count 9.0

Amide Bonds 49.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0028381 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Ovis aries [Animal]

FamilyMonoclonal antibody

Tax ID9606;9940

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Enzyme replacement

Half-Life12-23 hours [F113]