Peptide Database

Peptide NameNeuroparsin-A

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC368H569N107O116S13

DescriptionStandard

        NPISRSCEGANCVVDLTRCEYGDVTDFFGRKVCAKGPGDKCGGPYELHGKCGVGMDCRCGLCSGCSLHNLQCFFFEGGLPSSC
    

Molecular Weight8764.95 Da

Isoelectric Point (pI)6.06

Net Charge (pH 7.0)-1.17

Net Charge (pH 7.4) -1.67

Charge Density (pH 7.0) -0.0141

GRAVY Index-0.10

Hydrophobic Moment 0.56

Boman Index0.04

Instability Index26.49

Aliphatic Index 52.77

Aromaticity 0.0843

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3533.76

LogP -44.38

H-bond Donors 133.0

H-bond Acceptors 130.0

Rotatable Bonds 284.0

Heavy Atoms 604.0

Ring Count 13.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0320211 VERIFIED: NO

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

RECORD: Rec_0333237 VERIFIED: NO

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyNeuroparsin

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0382392 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/