‹ ›
MYP_003496
← PREVIOUS NEXT → BACK
Basic Information
Cryptdin-3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
35 amino acids
C174H301N65O45S8
Standard
Sequence
LRDLVCYCRKRGCKRRERMNGTCRKGHLMYTLCCR
Physicochemical Analysis
4280.18 Da
9.99
8.79
8.44
0.2510
-0.81
0.45
-0.50
42.98
52.86
0.0571
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1853.27
-19.97
77.0
63.0
149.0
292.0
3.0
35.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0141107 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]; Mammalia [Animal]
10090; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID1500163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1500163/
RECORD: Rec_0171659 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
6-34, 8-23, 13-33
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0198007 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID1500431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1500431/
RECORD: Rec_0223757 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-34; 8-23; 13-33
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
mouse-avirulent Salmonella typhimurium 7953
PaperPubMed PMID: 1500431 PMID1500431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1500431/
RECORD: Rec_0315406 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2