Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC550H884N148O162S3

DescriptionStandard

        PDLTGHEKFGLGNVKYNISRIHVTAVELPSASIFLLPGSGIKLVIGNASLTIDMNWNIRTWMFKDSGRGTVHISKVFVTAIFSTPLDNSGLTSIALTSCRTTPGDVDIKLNGKT
    

Molecular Weight12257.99 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.97

Charge Density (pH 7.0) 0.0282

GRAVY Index0.12

Hydrophobic Moment 0.54

Boman Index0.15

Instability Index19.50

Aliphatic Index 100.00

Aromaticity 0.0702

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4935.38

LogP -51.97

H-bond Donors 175.0

H-bond Acceptors 171.0

Rotatable Bonds 403.0

Heavy Atoms 863.0

Ring Count 18.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0146931 VERIFIED: NO

Provenance & Taxonomy

OrganismNesospiza acunhae [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria