MYP_003485
Neuropeptide S
Enzyme modulation
▸
Enzyme inhibition
▸
ACE inhibition
▸
ACE inhibitory
Immunology
▸
Immune modulation
▸
Immunomodulatory activity
Neurological / Signaling
▸
Neuromodulation
Neurological / Signaling
▸
Neuropeptide activity
▸
Neuropeptide
Neurological / Signaling
▸
Sleep regulation
Regulatory peptide
▸
Biological modulation
Regulatory peptide
▸
Biological regulation
Standard
20 amino acids
C95H160N34O27
Standard
SFRNGVGSGVKKTSFRRAKQ
2210.50 Da
12.00
5.46
5.25
0.2729
-1.03
0.49
-0.39
42.93
34.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1047.08
-15.00
39.0
33.0
78.0
156.0
2.0
21.0
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0112773
VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Neuropeptide S
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Neuromodulator
NPSR agonist
neuropeptide S receptor (NPSR)
3.2 nM
EC50 (NPSR activation / intracellular Ca2+ mobilization)
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0209340
VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Arousal/wake-promoting
Sleep regulation
mice; rats
behavioral arousal / sleep-wake assay
RECORD: Rec_0243885
VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Neuropeptide S
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Neuromodulator
Anxiolytic-like
mice
anxiety-like behavior assay