Peptide Database

Peptide NameCecropin

Function Ontology

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Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC119H202N40O32

DescriptionStandard

        GWLKKLGKRLERIGQHTRDATIQ
    

Molecular Weight2705.13 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.1673

GRAVY Index-1.03

Hydrophobic Moment 0.92

Boman Index-0.31

Instability Index20.12

Aliphatic Index 89.13

Aromaticity 0.0435

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1212.99

LogP -11.29

H-bond Donors 44.0

H-bond Acceptors 37.0

Rotatable Bonds 96.0

Heavy Atoms 191.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0328925 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila elegans [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)