MYP_003471
P1
Enzyme modulation
▸
Enzyme inhibition
Enzyme modulation
▸
Enzyme inhibition
▸
Thrombin inhibition
▸
Thrombin inhibitory
Hemostasis
▸
Anticoagulant activity
Hemostasis
▸
Antithrombotic activity
Standard
13 amino acids
C65H99N17O24
Standard
NDLWDQGLVSQDL
1502.58 Da
4.05
-3.24
-3.44
-0.2490
-0.58
0.21
0.01
57.08
112.31
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
689.71
-6.81
22.0
21.0
49.0
106.0
2.0
15.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0267864
VERIFIED: YES
Provenance & Taxonomy
Hirudo sp. [Animal]
Thrombin inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticoagulant
Antithrombotic
Enzyme inhibitory
Thrombin inhibitory
human thrombin
2425.5 ± 109.7 μM
IC50 (thrombin inhibition)
RECORD: Rec_0346650
VERIFIED: YES
Provenance & Taxonomy
Hirudo sp. [Animal]
thrombin inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiplatelet
Antithrombotic
platelets (aggregation assay)
platelet aggregation assay
RECORD: Rec_0431401
VERIFIED: YES
Provenance & Taxonomy
Hirudo sp. [Animal]
Thrombin inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticoagulant
Antithrombotic
plasma coagulation
thrombin time (TT) assay