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MYP_003432
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C35H53N7O11
Standard
Sequence
YQEPVL
Physicochemical Analysis
747.84 Da
4.05
-1.24
-1.44
-0.2064
-0.32
0.23
0.15
104.63
113.33
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
300.65
-0.89
9.0
10.0
21.0
53.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0062068 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
8.14 μM
IC50
PaperACE-inhibitory activity of probiotic yoghurt | Donkor, ON. et al. | DOI: 10.1016/j.idairyj.2007.02.009 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0092312 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
280 μM
IC50
PaperAngiotensin I Converting Enzyme Inhibitory Peptides Derived from Bovine Milk Proteins | Pihlanto-Leppala, A. et al. | DOI: 10.1016/S0958-6946(98)00048-X Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0115163 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
280 μM
IC50
RECORD: Rec_0122267 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 33.3%, C 66.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0174251 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperIdentification of angiotensin-I-converting enzyme inhibitory peptides derived from sodium caseinate hydrolysates produced by Lactobacillus helveticus NCC 2765 PMID15537298 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15537298/
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