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MYP_003426
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Basic Information
Bombolitin V
Antimicrobial
Antimicrobial ▸ Antibacterial
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
17 amino acids
C81H143N21O20
Standard
Sequence
INVLGILGLLGKALSHL
Physicochemical Analysis
1731.13 Da
8.76
0.85
0.59
0.0498
1.48
0.44
0.55
10.75
206.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
646.94
-2.94
22.0
22.0
59.0
122.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020073 VERIFIED: YES
Provenance & Taxonomy
Megabombus pennsylvanicus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
guinea pig erythrocytes
0.7±0.05 μg/mL
ED50 (Hemolysis)
PaperBombolitins, a new class of mast cell degranulating peptides from the venom of the bumblebee Megabombus pennsylvanicus. PMID2578459
RECORD: Rec_0029001 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0049365 VERIFIED: YES
Provenance & Taxonomy
Megabombus pennsylvanicus [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Mast-cell degranulating Histamine-releasing
rat peritoneal mast cells
2.0±0.3 μg/mL
ED50 (mast cell degranulation / histamine release)
PMID2578459 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2578459/
RECORD: Rec_0153124 VERIFIED: YES
Provenance & Taxonomy
Megabombus pennsylvanicus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
guinea pig erythrocytes
0.7±0.05 μg/mL
ED50 (Hemolysis)
PMID2578459 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2578459/
RECORD: Rec_0267523 VERIFIED: YES
Provenance & Taxonomy
Megabombus pennsylvanicus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Membrane-active Phospholipase A2-stimulating
phospholipase A2
phospholipase A2 stimulation assay
PMID2578459 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2578459/
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