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MYP_003391
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Basic Information
MiAMP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
76 amino acids
C354H523N105O106S6
Standard
Sequence
SAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNPFGWKSIFIQC
Physicochemical Analysis
8137.97 Da
9.08
4.57
4.16
0.0602
-0.32
0.53
0.04
17.78
40.00
0.1447
16960.00
17335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3406.07
-45.48
127.0
119.0
257.0
571.0
17.0
83.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184510 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Beta-Barrelin, Defensin
60698
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Yeast
Aspergillus fumigatus
100 μg/mL
IC50
PaperPubMed PMID 10543955 | PubMed PMID 9108242 | J.Mol.Biol. 1999; 293: 62 PMID10543955;9108242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10543955/
RECORD: Rec_0202450 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Beta-Barrelin, Defensin
60698
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Yeast
Ceratocystis paradoxa
75 μg/mL
IC50
PaperPubMed PMID 10543955 | PubMed PMID 9108242 | J.Mol.Biol. 1999; 293: 62 PMID10543955;9108242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10543955/
RECORD: Rec_0203695 VERIFIED: YES
Provenance & Taxonomy
Macadamia nut [Plant]; Insecta [Animal]
33090; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11738090 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11738090/
RECORD: Rec_0204092 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Beta-Barrelin, Defensin
60698
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Yeast
Alternaria helianthi
2月5日 μg/mL
IC50
PaperPubMed PMID 10543955 | PubMed PMID 9108242 | J.Mol.Biol. 1999; 293: 62 PMID10543955;9108242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10543955/
RECORD: Rec_0210891 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
11-64, 21-76, 23-49
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Sclerotinia sclerotiorum mycelia
50 μg/mL
MIC
PMID9108242;10543955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9108242/
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