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MYP_003391
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Basic Information
MiAMP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
76 amino acids
C354H523N105O106S6
Standard
Sequence
SAFTVWSGPGCNNRAERYSKCGCSAIHQKGGYDFSYTGQTAALYNQAGCSGVAHTRFGSSARACNPFGWKSIFIQC
Physicochemical Analysis
8137.97 Da
9.08
4.57
4.16
0.0602
-0.32
0.53
0.04
17.78
40.00
0.1447
16960.00
17335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3406.07
-45.48
127.0
119.0
257.0
571.0
17.0
83.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005348 VERIFIED: YES
Provenance & Taxonomy
Macadamia nut [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
A. heliarzthi, C. gloeosporioides, Fusarium oxysporum, L. maculans, P. grunzinicolu, S. sclerotiorum, V. dahlia, and Saccharomyces cerevisiae
2-5 μg/mL
IC50
PaperPurification, characterisation and cDNA cloning of an antimicrobial peptide from Macadamia integrifolia
RECORD: Rec_0008363 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperMarcus J.P., Green J.L., Goulter K.C., Harrison S.J., Manners J.M.;. "Purification, characterisation and cDNA cloning of an antimicrobial peptide from Macadamia integrifolia."; Eur. J. Biochem. 244:743-749.
RECORD: Rec_0009820 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Beta-Barrelin, Defensin
60698
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Yeast Anti-Gram-positive
Clavibacter michiganensis
10 μg/mL
IC50
PaperPubMed PMID 10543955 | PubMed PMID 9108242 | J.Mol.Biol. 1999; 293: 62 PMID10543955;9108242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10543955/
RECORD: Rec_0026389 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Beta-Barrelin, Defensin
60698
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Yeast
Alternaria helianthi
100 μg/mL
IC50
PaperPubMed PMID 10543955 | PubMed PMID 9108242 | J.Mol.Biol. 1999; 293: 62 PMID10543955;9108242 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10543955/
RECORD: Rec_0032882 VERIFIED: YES
Provenance & Taxonomy
Macadamia integrifolia [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
11-64, 21-76, 23-49
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pythium graminicola
5 μg/mL
MIC
PMID9108242;10543955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9108242/
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