Peptide Database

Peptide NameBrain-derived neurotrophic factor

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC582H944N176O176S9

DescriptionStandard

        HSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR
    

Molecular Weight13511.38 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)9.88

Net Charge (pH 7.4) 9.45

Charge Density (pH 7.0) 0.0830

GRAVY Index-0.63

Hydrophobic Moment 0.69

Boman Index-0.18

Instability Index37.38

Aliphatic Index 62.18

Aromaticity 0.0756

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5774.72

LogP -66.20

H-bond Donors 216.0

H-bond Acceptors 197.0

Rotatable Bonds 457.0

Heavy Atoms 943.0

Ring Count 17.0

Amide Bonds 124.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0195092 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide13-80; 58-109; 68-111

Bio-Activity Profile

Function

Cytokine Growth factor NGF-beta family Growth factor signaling