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MYP_003301
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Basic Information
LL-III/15
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C84H151N21O17
Standard
Sequence
VNFKKLLGKLLKVVK
Physicochemical Analysis
1727.23 Da
10.60
4.73
4.51
0.3153
0.48
0.71
0.06
-40.93
162.00
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
643.91
-1.27
22.0
22.0
64.0
122.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0121556 VERIFIED: YES
Provenance & Taxonomy
Lasioglossum laticeps [Animal]
Lasioglossin III
88510.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antimicrobial Antifungal
SW colon cells
42 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells | https://pubmed.ncbi.nlm.nih.gov/22100226/ PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0126051 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SW480
42 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0132860 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Lasioglossin analogue
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Anticancer
CCRF-CEM T
9 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0142724 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0145885 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Lasioglossin analogue
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Anticancer
SW480
42 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
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