Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length483 amino acids

Chemical FormulaC2370H3809N623O676S17

DescriptionStandard

        MAKGLDCRTRWATLVVLAALGTAVTEATNPGVVVRITQKGLDYACQQGVAALQKELEKIEIPPFSGSFKVKLLGKGEYSFYSMVIRGVQLPNSQIKLLPNEGLAVSVTNANVKMSGKWKARKNFIKVRGNFDLSVEGISISAGLKLSCDPTSGHSTATCSSCSSSIASVHLHISGSRLGWLIQLFQKKIESSLRNTMNSKICQVVTSSVSSKLEPFLQSVPVTAKIDNVAGIDYSLLAPPIATAETLDGQLKGEFFSLAHRSPPPFTPPPLAFPTDHDHMVYLGISDYFFNTAGLVYQQAGVLNLTLRDDMIPKESKFRLTTKYLGTLIPKVARMFPNMTVQLLVRVSSPPRLEVSPAGLALTPALEAQAFAVLPNSSLAPLFLLGMSTNVSVEVGAKSNRLVGQLGLDKLLLELKHSDIGPFSVELMQAVMNFVIPTAVLPKVNERLQKGFPLPLPRHVQLLNLVLQSYQDFLLFGADVQYD
    

Molecular Weight52391.47 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)11.17

Net Charge (pH 7.4) 10.36

Charge Density (pH 7.0) 0.0231

GRAVY Index0.15

Hydrophobic Moment 0.73

Boman Index0.14

Instability Index35.80

Aliphatic Index 103.52

Aromaticity 0.0725

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31775.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372229 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllostomus discolor [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria