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MYP_003294
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Basic Information
P90(derived from HCV polyprotein)
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
13 amino acids
C68H121N17O17
Standard
Sequence
KKKKVTAATYVLV
Physicochemical Analysis
1448.79 Da
10.18
3.76
3.54
0.2889
0.13
0.27
-0.02
-3.83
112.31
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
577.29
-3.50
21.0
21.0
50.0
102.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0030212 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Replication inhibition
Hepatitis C virus (HCV)
10 μM
% inhibition
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPeptide inhibitors of hepatitis C virus NS3 protease. | Portal-Núñez S, González-Navarro CJ, García-Delgado M, Vizmanos JL, Lasarte JJ, Borrás-Cuesta F. | Antivir Chem Chemother. 2003 Sep;14(5):225-33. | DOI:10.1177/095632020301400501 | PMID:14694985 PMID14694985 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14694985/
RECORD: Rec_0039124 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV)
70-80 % PR activity
PR activity
PMID14694985 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14694985/
RECORD: Rec_0068200 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Replication inhibition
Hepatitis C virus (HCV)
3 μM
% inhibition
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperPeptide inhibitors of hepatitis C virus NS3 protease. | Portal-Núñez S, González-Navarro CJ, García-Delgado M, Vizmanos JL, Lasarte JJ, Borrás-Cuesta F. | Antivir Chem Chemother. 2003 Sep;14(5):225-33. | DOI:10.1177/095632020301400501 | PMID:14694985 PMID14694985 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14694985/
RECORD: Rec_0088665 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPeptide inhibitors of hepatitis C virus NS3 protease. Antivir Chem Chemother. 2003 Sep;14(5):225-33. doi: 10.1177/095632020301400501. PMID: 14694985. PMID14694985 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14694985/
RECORD: Rec_0179455 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV)
PMID14694985 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14694985/
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