Peptide Database

Peptide NameAdipokinetic prohormone type 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC192H302N56O57S2

DescriptionStandard

        QLNFSTGWGRRYADPNADPMAFLTKLIQIEARKLSGCSN
    

Molecular Weight4370.92 Da

Isoelectric Point (pI)9.19

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0449

GRAVY Index-0.47

Hydrophobic Moment 0.54

Boman Index-0.06

Instability Index26.83

Aliphatic Index 70.26

Aromaticity 0.1026

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1853.80

LogP -20.32

H-bond Donors 65.0

H-bond Acceptors 61.0

Rotatable Bonds 143.0

Heavy Atoms 307.0

Ring Count 7.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176715 VERIFIED: NO

Provenance & Taxonomy

OrganismSchistocerca gregaria [Animal]

FamilyAKH/HRTH/RPCH

Tax ID7010

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsTrp8 Amidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone Metabolic

RECORD: Rec_0219538 VERIFIED: YES

Provenance & Taxonomy

OrganismSchistocerca gregaria [Animal]

FamilyAdipokinetic prohormone type

Tax ID7010

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Disulfide37-37

Other Mods8:Tryptophan amide

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0251422 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/