Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC726H1143N189O222S14

DescriptionStandard

        MNILMLTFIICGLLTQVTKGSFEPPKCWKNNIGHCRRRCLDTERYILLCRNKLSCCIYIIISHEYTRRPAFPMIHLEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETMTPETNTPETTMPPSETATSETMPPLSQTALTHN
    

Molecular Weight16519.89 Da

Isoelectric Point (pI)5.49

Net Charge (pH 7.0)-4.20

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0289

GRAVY Index-0.19

Hydrophobic Moment 0.60

Boman Index0.04

Instability Index65.89

Aliphatic Index 75.31

Aromaticity 0.0828

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6543.60

LogP -65.85

H-bond Donors 233.0

H-bond Acceptors 236.0

Rotatable Bonds 531.0

Heavy Atoms 1151.0

Ring Count 28.0

Amide Bonds 153.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327699 VERIFIED: NO

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyDefensin

Tax ID9598

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence