Peptide Database

Peptide NameMicasin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC173H263N53O49S6

DescriptionStandard

        GFGCPFNENECHAHCLSIGRKFGFCAGPLRATCTCGKQ
    

Molecular Weight4061.65 Da

Isoelectric Point (pI)8.35

Net Charge (pH 7.0)1.88

Net Charge (pH 7.4) 1.48

Charge Density (pH 7.0) 0.0494

GRAVY Index-0.13

Hydrophobic Moment 0.45

Boman Index0.05

Instability Index60.48

Aliphatic Index 38.68

Aromaticity 0.1053

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1620.20

LogP -19.90

H-bond Donors 61.0

H-bond Acceptors 59.0

Rotatable Bonds 129.0

Heavy Atoms 281.0

Ring Count 8.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0431396 VERIFIED: YES

Provenance & Taxonomy

OrganismMicrosporum canis [Fungus]

Structure & Mods

Configlinear peptide with disulfide constraints [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-25; 11-33; 15-35

Bio-Activity Profile

Function

Antimicrobial Antibacterial In vivo protective activity

TargetPseudomonas aeruginosa; mouse peritonitis model

Activity91.7±5.7 %

Methodmouse peritonitis survival assay

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