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MYP_003285
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Basic Information
Pumilarin (46-70)[T5K,Q8K,Y9K,G18K], Syn-Safencin-P56
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C142H245N43O31
Standard
Sequence
AGKEKIRKKLKNEIKKKWRKAVIAW
Physicochemical Analysis
3050.73 Da
10.84
8.79
8.59
0.3517
-1.20
0.68
-0.42
0.32
86.00
0.0800
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1268.97
-6.69
46.0
40.0
114.0
216.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0346056 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human keratinocytes HaCat
64 μg/mL
Cytotoxicity
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0356575 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Galleria mellonella
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0356686 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli NCTC 12923
2 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0375169 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCTC 9144
32 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
RECORD: Rec_0382633 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 15
128 μg/mL
MIC
PMID32566907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32566907/
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