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MYP_003257
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Basic Information
Tachystatin-B1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
42 amino acids
C214H319N67O56S6
Standard
Sequence
YVSCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF
Physicochemical Analysis
4918.63 Da
9.61
6.70
6.40
0.1595
-0.21
0.60
-0.15
67.40
34.76
0.2143
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2025.52
-23.25
84.0
69.0
154.0
343.0
10.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011920 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachystatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
P. pastoris
0.1 μg/mL
IC50
PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0020790 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 38.1%, T 33.3%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0162375 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachystatin
6853
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperJ Biol Chem. 1999 Sep 10;274(37):26172-8. | http://www.ncbi.nlm.nih.gov/pubmed/10473569 PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0164020 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Hemolytic
PMID10473569;17394123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0182028 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachystatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Candida albicans
3.0 μg/mL
IC50
PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
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