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MYP_003199
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Basic Information
Ranacyclin-B-AL1 (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
17 amino acids
C88H132N24O22S2
Standard
Sequence
AAFRGCWTKNYSPKPCL
Physicochemical Analysis
1942.27 Da
9.39
2.77
2.55
0.1631
-0.46
0.22
-0.04
37.81
34.71
0.1765
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
744.85
-6.57
28.0
27.0
57.0
136.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077446 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
26 μM
MIC
PMID21927839 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21927839/
RECORD: Rec_0140356 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
8292
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21927839 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21927839/
RECORD: Rec_0192480 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
51 μM
MIC
PMID21927839 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21927839/
RECORD: Rec_0196527 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0229407 VERIFIED: NO
Provenance & Taxonomy
Amolops loloensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
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