Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length236 amino acids

Chemical FormulaC1220H1846N272O357S7

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLNLKGIVYPAGNYTDPPYVAAPFTIPDQSESMLYLAFSEYFFQTFSFAYYTAGAFNVTIAEEVKSGKLIYFLTCFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLTAIEIPIISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTTNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight26259.77 Da

Isoelectric Point (pI)4.19

Net Charge (pH 7.0)-14.15

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0600

GRAVY Index0.40

Hydrophobic Moment 0.60

Boman Index0.27

Instability Index42.95

Aliphatic Index 102.50

Aromaticity 0.1441

Extinction Coeff. Reduced 19370.00

Extinction Coeff. Oxidized 19495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0262362 VERIFIED: NO

Provenance & Taxonomy

OrganismBuceros rhinoceros silvestris [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic

TargetGram-negative bacteria